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PTPN5 Antibody
PTPN5 Antibody
- 中文名称:
- PTPN5 Antibody
- 英文名称:
- PTPN5 Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA40537
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- PTPN5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Mouse
- 应用:
- IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:PTPN5 antibody is human and mouse reactive.
纯度:PTPN5 antibody is affinity chromatography purified via peptide column.
形式:Liquid
浓度:1 mg/mL
- 说明书:
The protein tyrosine phosphatase PTPN5, also known as Striatal enriched phosphatase (STEP), is involved in the regulation of synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors (1). It is expressed in dopaminoceptive neurons of the central nervous system and multiple forms of PTPN5 show differential enrichment in adult brain regions (2). NMDA-mediated activation of PTPN5 is an important mechanism for regulation of Erk activity in neurons (3). Furthermore, PTPN5 is involved in the regulation of both NMDAR and AMPAR trafficking (4,5). PTPN5 may play a role in Alzheimer's disease (1).