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SARS-CoV-2 UK Variant (B.1.1.7) Spike P681H Antibody
SARS-CoV-2 UK Variant (B.1.1.7) Spike P681H Antibody
- 中文名称：
- SARS-CoV-2 UK Variant (B.1.1.7) Spike P681H Antibody
- 英文名称：
- SARS-CoV-2 UK Variant (B.1.1.7) Spike P681H Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA40928
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- SARS-CoV-2 UK Variant (B.1.1.7) Spike P681H antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Virus
Predicted reactivity based on immunogen sequence: SARS-CoV Spike proteins: (25%)
- 应用：
- WB (Western Blot), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:N/A
纯度:SARS-CoV-2 (COVID-19) Alpha Variant (B.1.1.7, UK) Spike P681H Antibody is Protein A purified.
形式：Liquid. SARS-CoV-2 UK Variant (B.1.1.7) Spike P681H antibody is supplied in PBS containing 0.02% sodium azide.
浓度：1mg/mL
- 说明书：
In September of 2020 a new lineage of SARS-CoV-2, known as B.1.1.7, was discovered in the United Kingdom. This lineage was found to have developed 14 lineage-specific amino acid replacements and 3 deletions prior to its discovery. The transmission of UK variant (B.1.1.7 lineage) was increased at least 50%. Increased severity and higher death rate were also found in UK variant. UK variant will not affect the effectiveness of COVID19 vaccine. One of the mutations associated with this lineage is a N501Y in the spike protein of the virus. It is believed that this mutation is able to increase the spike protein's affinity for the host ACE2 receptor and it has been associated with increased infectivity and virulence. B.1.1.7 viruses have also been shown to have a P681H in the cleavage site of spike protein. This location is one of the residues that make up the furin cleavage site between S1 and S2 in spike protein.
