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Anti ATAT1 mouse monoclonal antibody
Anti ATAT1 mouse monoclonal antibody
- 中文名称:
- Anti ATAT1 mouse monoclonal antibody
- 英文名称:
- Anti ATAT1 mouse monoclonal antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA41075
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|5x0.1 mg|4x0.1 mg
- 保存建议:
- Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 4°C for frequent use. Store at -20 to -80°C for ~12 months from the date of receipt.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 应用:
- IHC (Immunohistochemistry), IF (Immunofluorescence), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1
克隆号:[77-D-12]
特异性:N/A
纯度:Protein G purified from mice ascites
形式:Liquid. Supplied as solution form in PBS, pH7.4, containing 0.05% Proclin300, 50% glycerol.
浓度:1.24 mg/ml
- 说明书:
Leads to drug resistance for microtubule-targeting drugs such as taxol and celastrol by downregulation of p53. DDX53 promotes autophagy by increasing expression of ATG5 via direct binding to the promoter of ATG5 in breast cancer cells. In addition, DDX53 shows co-expression with CD133, a cancer stemness marker, and is served as a new key regulator of cancer stem cell- like properties in taxol-resistant melanoma. Many evidences suggest that DDX53 is one of the attractive targets for developing anti-cancer drugs, there have not been reports concerning the role of DDX53 in cervix cancer.DDX53 (DEAD-Box Helicase 53) is a Protein Coding gene. Diseases associated with DDX53 include Colonic Disease and Gastric Adenosquamous Carcinoma. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and ATP-dependent RNA helicase activity.