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Anti-CS1 antibody (DM10), Rabbit mAb
Anti-CS1 antibody (DM10), Rabbit mAb
- 中文名称：
- Anti-CS1 antibody (DM10), Rabbit mAb
- 英文名称：
- Anti-CS1 antibody (DM10), Rabbit mAb
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47176
- 规格：
- 0.01 mg|0.1 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store at -20 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- IF (Immunofluorescence), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:Rabbit IgG
克隆号:[DM10]
特异性:N/A
纯度:Purified from cell culture supernatant by affinity chromatography
形式：Liquid; 0.1% Procline 300; 50% Glycerol; PBS, pH7.4; 0.1% BSA
浓度：N/A
- 说明书：
Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (PubMed:11698418). Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536). In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (By similarity). May play a role in lymphocyte adhesion (PubMed:11802771). In LPS-activated monocytes negatively regulates production of proinflammatory cytokines (PubMed:23695528).
