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Alpha-1-Antichymotrypsin Monoclonal Antibody
Alpha-1-Antichymotrypsin Monoclonal Antibody
- 中文名称：
- Alpha-1-Antichymotrypsin Monoclonal Antibody
- 英文名称：
- Alpha-1-Antichymotrypsin Monoclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47631
- 规格：
- 0.1 mg|0.5 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- These antibodies are stable for at least 1 year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- N/A
- 应用：
- IA (Immunoassay)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2a
克隆号:[1AC10-109.5]
特异性:These antibodies specifically recognize alpha-1-antichymotrypsin.They do not cross-react with alpha-1-antitrypsin.
纯度:N/A
形式：Clear liquid; Protein G-purified antibody in PBS, pH 7.4
浓度：0.8mg/ml
- 说明书：
Alpha 1-antichymotrypsin (α1AC) is an alpha globulin glycoprotein produced in the liver that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene. α1AC inhibits the activity of proteases such as cathepsin G from neutrophils and chymases from mast cells by cleaving them into different conformations. This activity protects tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes. α1AC is an acute phase protein that is induced during inflammation. Deficiency of this protein has been associated with liver disease, and mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. It is also associated with the pathogenesis of Alzheimer's disease as it enhances the formation of amyloid-fibrils.
