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Anti-Thymidylate Synthase Monoclonal Antibody
Anti-Thymidylate Synthase Monoclonal Antibody
- 中文名称:
- Anti-Thymidylate Synthase Monoclonal Antibody
- 英文名称:
- Anti-Thymidylate Synthase Monoclonal Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47650
- 规格:
- 0.2 mg|2x0.2 mg|3x0.2 mg|4x0.2 mg|5x0.2 mg
- 保存建议:
- This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- N/A
- 应用:
- IP (Immunoprecipitation), IHC (Immunohistochemistry), IB (Immunoblot), ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1
克隆号:N/A
特异性:Anti-Thymidylate Synthase [Murine MAb to human thymidylate synthase, a drug resistance-associated enzyme.]
These antibodies specifically recognize human TS (36 kDa). They do not crossreact with rat TS.
纯度:N/A
形式:200 ug Protein G-purified antibody in PBS, pH 7.4.
浓度:N/A
- 说明书:
Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.