-
FKBP52 Monoclonal Antibody
FKBP52 Monoclonal Antibody
- 中文名称：
- FKBP52 Monoclonal Antibody
- 英文名称：
- FKBP52 Monoclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47735
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- N/A
- 应用：
- IP (Immunoprecipitation), IHC (Immunohistochemistry), IB (Immunoblot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:N/A
特异性:FKBP52 Monoclonal Antibody [Mouse monoclonal antibody recognizes FKBP52 of multiple species.]
This antibody recognizes human, mouse, rat, dog, and hamster FKBP52.
纯度:N/A
形式：100ug in PBS, pH 7.4, purified by Protein G affinity chromatography.
浓度：N/A
- 说明书：
FK506-binding proteins, FKBP51 and FKBP52, are high molecular weight immunophilins that are part of the mature glucocorticoid receptor heterocomplex. The N-terminal domains of these proteins bind FK506 and have peptidyl-prolyl isomerase activity that converts prolyl peptide bonds within target proteins from cis- to trans- proline. The C-terminal domains contain the tetratricopeptide repeats that are involved in protein-protein interactions with Hsp90. Although FKBP52 and FKBP51 share ~75% sequence similarity, they affect hormone binding by glucocorticoid receptors differently and have different Hsp90-binding characteristics. In addition, FKBP51 is linked to the progesterone receptor while FKBP52 is linked to progesterone, androgen, and glucocorticoid receptors.
