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Anti-Shank3 Monoclonal Antibody
Anti-Shank3 Monoclonal Antibody
- 中文名称:
- Anti-Shank3 Monoclonal Antibody
- 英文名称:
- Anti-Shank3 Monoclonal Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47744
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human, mouse, rat
- 应用:
- IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), IB (Immunoblot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG2b
克隆号:[S69-46]
特异性:Shank3
This antibody recognizes human, mouse, and rat Shank3. It does not cross-react with Shank1 or Shank2.
纯度:N/A
形式:100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.
浓度:N/A
- 说明书:
Shank proteins are a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Shank proteins are crucial in receptor tyrosine kinase signaling; specifically, Shank3 can mediate Erk-MAPK and P13K signaling which is crucial for tubule formation. Shank 3 is also one of the latest genes to be associated with autism. A mutation in a single copy of Shank3 on chromosome 22q13 can result in communication disorders.