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K+/Cl- Cotransporter (KCC2) Monoclonal Antibody
K+/Cl- Cotransporter (KCC2) Monoclonal Antibody
- 中文名称:
- K+/Cl- Cotransporter (KCC2) Monoclonal Antibody
- 英文名称:
- K+/Cl- Cotransporter (KCC2) Monoclonal Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47757
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- N/A
- 应用:
- IHC (Immunohistochemistry), IB (Immunoblot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1
克隆号:N/A
特异性:This antibody recognizes human, mouse and rat KCC2.
纯度:N/A
形式:N/A
浓度:N/A
- 说明书:
KCC2 is a member of the cation-chloride cotransporter gene family. KCCs lower intracellular chloride concentrations below the electrochemical equilibrium potential. Depending on the concentration gradients of potassium and chloride, KCC2 can operate as a net efflux or influx pathway. KCC2 is expressed at high levels in neurons throughout the nervous system and is localized at inhibitory synapses of the spinal cord. Studies in mice have shown that KCC2 reduces GABAs inhibitory signaling resulting in motor defects, epilepsy, and anxiety-like behavior.