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Transglutaminase-3 (TG3) Monoclonal Antibody
Transglutaminase-3 (TG3) Monoclonal Antibody
- 中文名称：
- Transglutaminase-3 (TG3) Monoclonal Antibody
- 英文名称：
- Transglutaminase-3 (TG3) Monoclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47773
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- This product is stable for at least one (1) year at -20 degree C to -70 degree C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- N/A
- 应用：
- ICC (Immunocytochemistry), IB (Immunoblot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:N/A
特异性:This antibody recognizes full-length human TG3 (77kDa) and the proteolysed form of human TG3 (30-47kDa).
纯度:N/A
形式：100ug, Protein A-purified, lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.
浓度：N/A
- 说明书：
Transglutaminase-3 (TG3), an epidermal-type enzyme, is responsible for formation of the epidermis. During keratinocyte differentiation, TG1 and TG3 appear to act cooperatively in the cross-linking of proteins, including involucrin, loricrin and small proline-rich proteins (SPRs). These reactions result in formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Furthermore, TG3 in hair follicles is involved in cross-linking structural proteins such as trichohyalin and keratin intermediate to hardening the inner root sheath. During differentiation in these processes, a zymogen form of TG3 (77 kDa) is activated by limited proteolysis with cathepsins S and/or L.
