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Atg4C
Atg4C
- 中文名称：
- Atg4C
- 英文名称：
- Atg4C
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47778
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- This antibody is stable for at least one (1) year at -20 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- N/A
- 应用：
- IB (Immunoblot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:This antibody recognizes human and rat Atg4C
纯度:N/A
形式：Peptide affinity-purified antibody in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
浓度：1mg/ml
- 说明书：
Autophagy is a catabolic process that results in the degradation of bulk cytoplasmic contents within autophagosomes and lysosomes. Recent studies demonstrated that Atg4D is a substrate for caspase-3 during apoptosis. Truncated Atg4D has increased priming and delipidation effects on the Atg8 paralogue GABARAP-L1 in vitro and induces cell death when overexpressed in human cells. In addition, Atg4D-mediated apoptosis is facilitated by a putative C-terminal BH3 domain and is preceded by recruitment of Atg4D to mitochondria, suggesting that Atg4D plays an important role at the interface between autophagy and apoptosis.
