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UVRAG
UVRAG
- 中文名称：
- UVRAG
- 英文名称：
- UVRAG
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47785
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- This antibody is stable for at least one (1) year at -20 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- N/A
- 应用：
- IF (Immunofluorescence), IB (Immunoblot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:This antibody recognizes human and rat UVRAG.
纯度:N/A
形式：Peptide affinity-purified antibody in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
浓度：1mg/ml
- 说明书：
Autophagy is a catabolic process that results in the degradation of bulk cytoplasmic contents within autophagosomes and lysosomes. UV radiation resistance-associated gene product (UVRAG) is a protein localized in the endoplasmic reticulum (ER) and endosomes and is known to regulate autophagosome maturation as well as early stages of autophagy. UVRAG regulates autophagosome maturation by binding to the homotypic fusion and vacuole protein sorting (HOPS) complex, which consists of the class C Vps complex (Vps11-Vps16-Vps18-Vps33) and two additional proteins, Vps39 and Vps41. UVRAG binding to the HOPS complex stimulates lysosomal fusion with autophagosome and endosome.
