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Adenosine deaminase Monoclonal Antibodies
Adenosine deaminase Monoclonal Antibodies
- 中文名称：
- Adenosine deaminase Monoclonal Antibodies
- 英文名称：
- Adenosine deaminase Monoclonal Antibodies
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47858
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- These antibodies are stable for at least one (1) year at-20 degree C. Store in appropriate aliquots to avoid multiple freeze-thaw cycles
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- N/A
- 应用：
- ELISA, IB (Immunoblot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:N/A
克隆号:N/A
特异性:Native and recombinant ADA.
纯度:N/A
形式：Protein G-purified antibody in PBS, pH 7.4.
浓度：N/A
- 说明书：
Adenosine deaminase (ADA) is a purine catabolic enzyme which irreversibly deaminates adenosine and deoxyadenosine. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. ADA deficiency (due to mutations in the ADA gene) results in severe combined immunodeficiency (SCID) as a result of accumulation of deoxyadenosine which, in turn, leads to (1) a buildup of dATP which inhibits ribonucleotide reductase and prevents DNA synthesis; since developing T cells and B cells are some of the most mitotically active cells, they are highly susceptible to this condition, and (2) an increase in Sadenosylhomocysteine since ADA is important in the purine salvage pathway; both substances are toxic to immature lymphocytes, which thus fail to mature.
