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Anti-Neurturin Antibody
Anti-Neurturin Antibody
- 中文名称：
- Anti-Neurturin Antibody
- 英文名称：
- Anti-Neurturin Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47907
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- N/A
- 应用：
- IB (Immunoblot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:N/A
同型:N/A
克隆号:N/A
特异性:Anti-Neurturin [Rabbit antibody to peptide corresponding to aa 178-193 of human neurturin.]
This antibody recognizes human, neurturin (14 kD).
纯度:N/A
形式：100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
浓度：N/A
- 说明书：
Glial cell line-derived neurotrophic factor (GDNF) plays a key role in the conrol of vertebrate neuron survival and differentiation. A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin. (NTN). Physiological responses to NTN require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNR alpha . The cDNAS encoding NTNR alpha from human, rat, chicken, and mouse have been cloned and referred to as GFR alpha -2, GDNFR beta , Ret ligand 2 (RETL2), and TGF- beta -related neurotrophic factor receptor 2 (TmR2). NTN forms a complex with GFR alpha -2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway. Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations.
