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Anti-p38 Polyclonal Antibody
Anti-p38 Polyclonal Antibody
- 中文名称:
- Anti-p38 Polyclonal Antibody
- 英文名称:
- Anti-p38 Polyclonal Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47935
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- N/A
- 应用:
- IP (Immunoprecipitation), IB (Immunoblot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:p38 Antibody [Rabbit antibody recognizes p38 of multiple species]
This antibody recognizes human, mouse, rat, bovine, chicken, dog, guinea pig, hamster, pig, monkey, rabbit, and sheep p38.
纯度:N/A
形式:100ul whole antiserum
浓度:N/A
- 说明书:
The MAPK (mitogen-activated protein kinase) family includes stress-activated protein kinases (SAPKs), extracellular signal-regulated kinases (ERKs), and p38 kinases. Upon activation, p38 translocates to the cell nucleus where it phosphorylates one or more nuclear substrates resulting in transcriptional changes and other cellular processes involved in cell growth, division, differentiation, inflammation, and death. p38 always acts as a pro-apoptotic factor with its activation leading to the release of cytochrome c from mitochondria and cleavage of caspase-3 and its downstream effector PARP. p38 is activated by chemical stress inducers (such as hydrogen peroxide and heavy metals) and biological stress signals (such as tumor necrosis factor, interleukin-1, irradiation, and chemotherapeutic drugs).