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Anti-ERK1/2 Polyclonal Antibody
Anti-ERK1/2 Polyclonal Antibody
- 中文名称：
- Anti-ERK1/2 Polyclonal Antibody
- 英文名称：
- Anti-ERK1/2 Polyclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47939
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- This antibody is stable for at least one (1) year at -20°C. Avoid repeated freezing and thawing.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- N/A
- 应用：
- IB (Immunoblot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:This antibody recognizes human, mouse, rat, bovine, chicken, sheep, Drosophila, and Xenopus ERK1/2.
纯度:N/A
形式：Serum
浓度：N/A
- 说明书：
The extracellular signal-regulated kinases 1 and 2 (ERK1/2) are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. The 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, so they are referred to collectively as ERK1/2. They are both found in the cytosol and mitochondria. ERK 1 and 2 are activated by MEK1 or MEK2 by dual phosphorylation of a threonine and tyrosine residue in the activation loop. Once activated, these kinases phosphorylate a variety of substrates including cytoskeletal proteins, translation regulators, transcription factors, and the Rsk family of protein kinases. ERK1/2 activation is believed to confer a survival advantage to cells but may also contribute to cell death under certain conditions.
