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GRP78/HSPA5
GRP78/HSPA5
- 中文名称：
- GRP78/HSPA5
- 英文名称：
- GRP78/HSPA5
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48337
- 规格：
- 0.05 mL|0.1 mL|2x0.1 mL|5x0.05 mL|3x0.1 mL
- 保存建议：
- Can be stored at 2 degree C to 8 degree C for 1 week. For long term storage, aliquot and store at -20 degree C to -80 degree C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1 kappa
克隆号:[AT3D2]
特异性:N/A
纯度:By protein-A affinity chromatography
形式：Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol
浓度：1mg/ml
- 说明书：
Binding immunoglobulin protein (BIP) also known as 78kDa glucose-regulated protein (GRP-78) or heatshock 70kDa protein 5 (HSPA5) is a HSP70 molecular chaperone located in the lumen of the endoplasmicreticulum (ER) that binds newly synthesized proteins as they are translocated into the ER, and maintains themin a state competent for subsequent folding and oligomerization. BIP is also an essential component of thetranslocation machinery, as well as playing a role in retrograde transport across the ER membrane of aberrantproteins destined for degradation by the proteasome. BIP is an abundant protein under all growth conditions, butits synthesis is markedly induced under conditions that lead to the accumulation of unfolded polypeptides in theER.
