-
MOUSE ANTI HUMAN GLUCOCORTICOID RECEPTOR:FITC
MOUSE ANTI HUMAN GLUCOCORTICOID RECEPTOR:FITC
- 中文名称：
- MOUSE ANTI HUMAN GLUCOCORTICOID RECEPTOR:FITC
- 英文名称：
- MOUSE ANTI HUMAN GLUCOCORTICOID RECEPTOR:FITC
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA49104
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- The product is shipped at ambient tempeture. It is recommended to aliquot and store at -20°C on receipt. When thawed , aliquot the smaple as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks)and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Mouse
- 应用：
- FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:[5E4]
特异性:N/A
纯度:Purified IgG prepared by ion exchange chromatography from tissue culture supernatant
形式：FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC)-Liquid
Phosphate buffered saline
浓度：IgG concentration 0.1 mg/ml
- 说明书：
Mouse anti Human Glucocorticoid Receptor antibody, clone 5E4 recognizes the human glucocorticoid receptor, also known as Nuclear receptor subfamily 3 group C member 1 (NR3C1), a 777 amino acid receptor bearing 3 distinct functional domains, an N-terminal modulating domain, a DNA binding domain and a C-terminal steroid binding domain. The human glucocorticoid receptor is located either in the cytoplasm of cells, prior to ligand binding associated with certain heat shock proteins (Kino et al. 2009), or the nucleus following binding to ligand (Werb et al. 1978). Mutations in the glucocorticoid receptor gene can lead to familial glucocorticoid resistance, characterized by elevated plasma cortisol levels (Malchoff et al. 1993). Mouse anti human glucocorticoid receptor antibody, clone 5E4 has been demonstrated to cross-react with the murine glucocorticoid receptor (Bergquist et al. 2014)
