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MOUSE ANTI HUMAN C3c
MOUSE ANTI HUMAN C3c
- 中文名称：
- MOUSE ANTI HUMAN C3c
- 英文名称：
- MOUSE ANTI HUMAN C3c
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA49392
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- N/A
- 应用：
- WB (Western Blot), FCM/FACS (Flow Cytometry), ELISA, IHC (Immunohistochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:[013E-498.2.3 (10-02A)]
特异性:C3c
纯度:N/A
形式：Purified IgG-Liquid
浓度：Current batch-specific concentration 1.2mg/mL.
- 说明书：
Mouse anti human C3c, clone 10-02A, recognizes 135kDa complement component 3c present in blood serum. C3c is generated over the course of complement activation, where convertase C4b2a (classical pathway) and convertase C3bBb (alternative pathway) cleave C3 to C3b and C3a. C3b is further degraded into iC3b and C3dg/C3d. iC3b is then slowly cleaved (possibly by factor I) to form C3c (beta chain + alpha' chain fragment 1 + alpha' chain fragment 2), C3dg and C3f. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
