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MOUSE ANTI HUMAN PAPILLOMAVIRUS 16 ONCOPROTEIN E7
MOUSE ANTI HUMAN PAPILLOMAVIRUS 16 ONCOPROTEIN E7
- 中文名称：
- MOUSE ANTI HUMAN PAPILLOMAVIRUS 16 ONCOPROTEIN E7
- 英文名称：
- MOUSE ANTI HUMAN PAPILLOMAVIRUS 16 ONCOPROTEIN E7
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA49545
- 规格：
- 0.2 mg|2x0.2 mg|3x0.2 mg|4x0.2 mg|5x0.2 mg
- 保存建议：
- It is recommended to aliquot and store at -20 degree C on receipt.
When thawed, aliquot the sample as needed. Keep aliquots at 2-8 degree C for short term use (up to 4 weeks) and store the remaining aliquots at -20 degree C.
Avoid repeated freezing and thawing as this may denature the antibody.
Storage in frost-free freezers is not recommended
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- N/A
- 应用：
- WB (Western Blot), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2a
克隆号:[716-D1]
特异性:N/A
纯度:Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
形式：Purified IgG - liquid
浓度：IgG concentration 1.0 mg/ml
- 说明书：
Mouse anti Human Papillomavirus 16 Oncoprotein E7 antibody, clone 716-D1 recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-supressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. Mouse anti Human Papillomavirus 16 Oncoprotein E7 antibody, clone 716-D1 cross-reacts with both the monomer and dimer forms of the E7 protein of HPV-18.
