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MOUSE ANTI RABBIT T LYMPHOCYTES:FITC
MOUSE ANTI RABBIT T LYMPHOCYTES:FITC
- 中文名称：
- MOUSE ANTI RABBIT T LYMPHOCYTES:FITC
- 英文名称：
- MOUSE ANTI RABBIT T LYMPHOCYTES:FITC
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA49708
- 规格：
- 100 Tests|2x100 Tests|3x100 Tests|4x100 Tests|5x100 Tests
- 保存建议：
- Store at 4 degree C for one month or at -20 degree C for longer. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- N/A
- 应用：
- FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:[KEN-5]
特异性:N/A
纯度:N/A
形式：FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
浓度：IgG concentration 0.1 mg/ml
- 说明书：
Mouse anti Rabbit T-Lymphocytes, clone KEN-5, specifically recognizes rabbit (lapine)T cells. Clone KEN-5 recognizes >90% thymocytes and approximately 40-45% mesenteric lymph node cells and immunoprecipitates a 67kDa protein from rabbit thymocytes. In contrast to Humans and Mice where only a very small population of B-cells express the CD5 antigen, the CD5 antigen in Rabbits is widely expressed by peripheral blood B-cells. However, the KEN-5 antibody, while originally reported as recognising rabbit CD5 (Kotani et al.1993), does not bind to rabbit CD5 transfectants. Furthermore, clone KEN-5, unlike other known antibodies recognising rabbit CD5 and anti human cross reactive CD5 antibodies, shows very limited binding to rabbit B lymphocytes, which in adult rabbits have been demonstrated to express CD5 (Raman & Knight 1992) More recently studies (Pospisil et. al. 2009) indicate that clone KEN-5 may recognize a epitope that is dependant on glycosylation to maintain its structural configuration which may explain why this antibody does not recognize recombinant rabbit CD5 produced in insect cells which contain different glycans from those found in mammalian cells. It has therefore been suggested that KEN-5 may distinguish between different isoforms of CD5 in lapine T and B cells (Pospisil et. al. 2009).
