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Rabbit Polyclonal to Human XAF1
Rabbit Polyclonal to Human XAF1
- 中文名称:
- Rabbit Polyclonal to Human XAF1
- 英文名称:
- Rabbit Polyclonal to Human XAF1
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA50698
- 规格:
- 0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg|5x0.05 mg
- 保存建议:
- Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Mouse
- 应用:
- WB (Western Blot), IHC (Immunohistochemistry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:synthetic peptide corresponding to amino acids at the C-terminus of human XAF-1
纯度:Immunoaffinity Purified
形式:PBS, 0.02% sodium azide.
浓度:1 mg/ml
- 说明书:
XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death. XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines. In contrast, XIAP levels have been shown to be high in a majority of cell lines.