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Mouse Anti-Human IL-8 Monoclonal Antibody,Azide Free Clone B-K8
Mouse Anti-Human IL-8 Monoclonal Antibody,Azide Free Clone B-K8
- 中文名称：
- Mouse Anti-Human IL-8 Monoclonal Antibody,Azide Free Clone B-K8
- 英文名称：
- Mouse Anti-Human IL-8 Monoclonal Antibody,Azide Free Clone B-K8
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA58559
- 规格：
- 0.2 mg|0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg
- 保存建议：
- Store at +2-8 degree C for 12 months. For longer storage, freeze aliquots.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- FA (Functional Assay), ELISA, FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:Mouse IgG1 Kappa light chain
克隆号:[B-K8]
特异性:Recognises both natural and recombinant human IL-8
纯度:Ion exchange chromatography
形式：Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
浓度：N/A
- 说明书：
Interleukin 8 (IL-8) or CXCL8, Monocyte-Derived Neutrophil Chemotactic Factor (MDNCF), Neutrophil Activating Factor (NAF) and NAD-P1 is a chemokine secreted by monocytes, macrophages and endothelial cells. IL-8 chemoattracts and activates neutrophils.
The predominant form of IL-8 is a 8.4kDa protein containing 72 amino acid residues, which includes five additional N-Terminal amino-acids. IL-8 contains the four conserved cysteine residues present in CXC chemokines and also contains the “ELR” motif common to CXC chemokines that binds to CXCR1 and CXCR2.
Data indicate that IL-8 may participate in the pathogenesis of rheumatoid arthritis via the induction of neutrophil-mediated cartilage damage, and psoriasis. A causative involvement of IL-8 is found within a broad range of clinico-pathological conditions : adult respiratory distress syndrome, asthma, bacterial infections, bladder cancer, graft rejection and influenza infection, due to the now known biological properties of IL-8. This cytokine especially in combinations with other neutrophil activating agents, may prove helpful in the treatment of patients suffering from granulocytopenia, severe infections against which antibiotics are not effective, and immunodeficiency caused by HIV.
