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Meprobamate
Meprobamate
- 中文名称：
- Meprobamate
- 英文名称：
- Meprobamate
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA58681
- 规格：
- 1 mg|10 mg|2x10 mg|3x10 mg|4x10 mg
- 保存建议：
- Upon delivery aliquot and store at -20 degree C. Avoid freeze / thaw cycles. Short term storage 2 - 8 degree C.
- 货期：
- 6-8周
- 来源宿主：
- Sheep
- 反应种属：
- N/A
- 应用：
- IA (Immunoassay), IHC (Immunohistochemistry), DB (Dot Blot), WB (Western Blot), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:N/A
形式：Ig Fraction - Liquid
浓度：>5mg/ml (U.V.abs @ 280nm)
- 说明书：
Meprobamate (marketed under the brand names Miltown by Wallace Laboratories, Equanil by Wyeth, and Meprospan) is a carbamate derivative which is used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benzodiazepines. Although it was marketed as being safer, meprobamate has most of the pharmacological effects and dangers of the barbiturates (though it is less sedating at effective doses). It is reported to have some anticonvulsant properties against absence seizures, but can exacerbate generalized tonic-clonic seizures. Meprobamate's mechanism of action is not completely known. It has been shown in animal studies to have effects at multiple sites in the central nervous system, including the thalamus and limbic system. Meprobamate binds to GABAA receptors which interrupts neuronal communication in the reticular formation and spinal cord, causing sedation and altered perception of pain. It has been shown that meprobamate has the ability to activate currents even in the absence of GABA. It is also a potent adenosine reuptake inhibitor (AdoRI).
