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CTLA-4 Antibody
CTLA-4 Antibody
- 中文名称：
- CTLA-4 Antibody
- 英文名称：
- CTLA-4 Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA58783
- 规格：
- 0.1 mL (Concentrate)|7 mL (RTU)|1 mL (Concentrate)|5x7 mL (RTU)|2x1 mL (Concentrate)
- 保存建议：
- Store at 2-8°C. To ensure stability, immediately replace vial back in the refrigerator after each use. When stored correctly, the antibody is stable until the expiry date indicated on the label. Positive and negative controls should be concurrently run with tissue specimens, to enable identification of any inadequacies with the antibody or reagents.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:N/A
形式：N/A
浓度：N/A
- 说明书：
The CTLA-4 [IHC064] antibody is intended for qualified laboratories to qualitatively identify by light microscopy, the presence of associated antigens in formalin-fixed, paraffin-em~edded (FFPE) tissue sections using immunohistochemistry test methods. Use of this antibody is indicated as an aid in the identification of CTLA-4 strictly for research purposes.
Background: Cytotoxic T-Lymp ocyte-AssOCiated-Protein 4 (CTLA-4jlSa receptor on T helper cells that functions as an immune checkpoint and downregulator of immune responses. Mutations In CTLA-4 are associated with insulin-dependent diabetes mellitus, Hashimoto's thyroiditis, Graves' disease, systemic lupus erythematosis, celiac disease, primary biliary cirrhosis, thyroid-associated orbitopathy, multiple sclerosis, and other autoimmune diseases. The spliced varient of CTLA-4 in SLE is present in the patient's serum. Haploinsufficiency of CTLA-4 causes the immune system disorder known as CTLA-4 deficiency or CHAI disease (CTLA-4 haploinsufficiency with autoimmune infiltration).
