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CD123
CD123
- 中文名称：
- CD123
- 英文名称：
- CD123
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA58798
- 规格：
- 0.1 mL (Concentrate)|7 mL (RTU)|1 mL (Concentrate)|5x7 mL (RTU)|2x1 mL (Concentrate)
- 保存建议：
- 请按照说明书指示
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:N/A
形式：N/A
浓度：N/A
- 说明书：
Cluster of Differentiation 123 (CD123), also known as Interleukin-3 Receptor, plays an important role in regulating the immune system by transmitting interleukin-3 signals, thereby promoting proliferation and differentiation of hematopoietic stem cells. Studies suggest that the expression of CD123 is observed in most Acute Myeloid Leukemia (AML) subtypes, including leukemic stem cells. CD123 positive AML has demonstrated higher marrow blast percentages and monocytic differentiation, and clinical presentations for AML mostly include bone marrow involvement and regional lymphadenopathy. As there are overlapping clinical presentations between AML and blastic NK-cell lymphomas, differential identification is important; use of a panel of CD123, CD4, CD56, and TCL-1 can help with this distinguishment between AML and myeloid involvement from blastic NK-cell lymphomas.
