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CD73
CD73
- 中文名称:
- CD73
- 英文名称:
- CD73
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA58802
- 规格:
- 0.1 mL (Concentrate)|7 mL (RTU)|1 mL (Concentrate)|2x1 mL (Concentrate)|3x1 mL (Concentrate)
- 保存建议:
- 请按照说明书指示
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1, Kappa
克隆号:N/A
特异性:N/A
纯度:N/A
形式:N/A
浓度:N/A
- 说明书:
Cluster of Differentiation 73 (CD73), also known as Ecto-5'-Nucleotidase (ecto-5'-NT), is a cell surface enzyme found in most tissues. CD73 catalyzes the breakdown of AMP to adenosine, thereby modulating inflammatory and T-cell responses. Reports have implicated CD73 expression in tumour progression and carcinogenesis, as CD73 is a key regulatory molecule in the proliferation, migration, and invasion of cancer cells in vitro, as well as tumour angiogenesis and tumour immune escape in vivo. Due to this key involvement in cancer, CD73 has become an appealing target for cancer immunotherapy. CD73 expression has also been linked to favourable prognosis in breast carcinoma.