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Calponin
Calponin
- 中文名称：
- Calponin
- 英文名称：
- Calponin
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59176
- 规格：
- 5 Slides|0.1 mL (Concentrate)|3 mL (RTU)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议：
- Store at 2 to 8 degree C in the dark.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human, Canine, Feline
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1/K
克隆号:[CALP-A6]
特异性:N/A
纯度:N/A
形式：Anti-Calponin (CALP-A6) is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
浓度：N/A
- 说明书：
Calponin is a 34 kDa polypeptide that interacts with actin, tropomyosin, and calmodulin. It is involved in smooth-muscle contraction mechanisms and is restricted exclusively to smooth-muscle tissue. Calponin is a calcium-binding protein. Calponin tonically inhibits the ATPase activity of myosin in smooth muscle. Phosphorylation of calponin by a protein kinase (which is dependent upon calcium binding to calmodulin) releases the calponin's inhibition of the smooth-muscle ATPase. Calponin has been found to be useful in differentiating benign sclerosing lesions of the breast from Carcinoma. Calponin positivity has also been noted in Malignant Myoepithelioma and Pleomorphic Adenoma of Salivary Gland origin, as well as in Angiomatoid Malignant Fibrous Histiocytoma.
