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CD43
CD43
- 中文名称:
- CD43
- 英文名称:
- CD43
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59189
- 规格:
- 5 Slides|3 mL (RTU)|0.1 mL (Concentrate)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议:
- Store at 2 to 8 degree C in the dark.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1
克隆号:[MT1]
特异性:N/A
纯度:N/A
形式:CD43 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
浓度:N/A
- 说明书:
CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) is one of the major glycoproteins expressed in all thymocytes and T-cells. It plays a role in the physicochemical properties of the T-cell surface and in lectin binding. During T-cell activation, CD43 is actively removed from the T-cell antigen-presenting cell contact site, suggesting a negative regulatory role in adaptive immune response. This antibody has been found useful in identification and classification of T-cell malignancies and low grade B-cell Lymphomas. CD43 expression is seen in some cases of B-cell Lymphocytic Lymphoma and Centrocytic Lymphoma. When used in combination with CD45 and CD20, effective immunophenotyping of the majority of Lymphomas can be obtained. Co-staining of a lymphoid infiltrate with CD20 and CD3 argues against a reactive process and favors Lymphoma.