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CD74
CD74
- 中文名称：
- CD74
- 英文名称：
- CD74
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59197
- 规格：
- 5 Slides|3 mL (RTU)|0.1 mL (Concentrate)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议：
- Store at 2 to 8 degree C in the dark.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:[LN2]
特异性:N/A
纯度:N/A
形式：CD74 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
浓度：N/A
- 说明书：
CD74, also known as the MHC Class II-associated invariant chain (II), is a Type II transmembrane protein which binds to the peptide-binding groove of newly-synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen-presenting cells such as B-lymphocytes (from before the pre-B-cell stage to before the plasma-cell stage), macrophages and monocytes, together with many epithelial cells. CD74 stains predominantly germinal-center lymphocytes and B-cell lymphomas but rarely T-cell lymphomas. It stains the cell membrane but a paranuclear globular labeling is also noted. CD74 is useful in differentiating Atypical Fibroxanthoma from Malignant Fibrous Histiocytoma, as well as Small-cell Lung Carcinoma from Non-small cell Lung Carcinomas.
