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COX-2 RMab
COX-2 RMab
- 中文名称:
- COX-2 RMab
- 英文名称:
- COX-2 RMab
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59204
- 规格:
- 5 Slides|3 mL (RTU)|0.1 mL (Concentrate)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议:
- Store at 2 to 8°C. (Control Slides: Store at 20-25°C)
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Dog, Cat, Mouse, Rat
- 应用:
- IHC (Immunohistochemistry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG
克隆号:[RBT-COX2]
特异性:N/A
纯度:N/A
形式:COX-2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
浓度:N/A
- 说明书:
Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, Cyclooxygenase (COX) is an enzyme that is responsible for formation of important biological mediators called prostanoids (including prostaglandins, prostacyclin and thromboxane). Pharmacological inhibition of COX can provide relief from the symptoms of inflammation and pain; this is the method of action of well-known drugs such as aspirin and ibuprofen. COX-2 inhibition by nonsteroidal anti-inflammatory agents has been shown to decrease angiogenesis and tumor growth, and promote apoptosis. COX-2 overexpression has been associated with increased microvascular density, and VEGF protein expression in head and neck Squamous-cell Carcinomas and is a poor prognostic indicator in this entity as well. COX-2 overexpression has also been suggested as a poor prognostic indicator in Carcinomas of the colon, breast, pancreas, and Adenocarcinomas of the lung.