-
p53
p53
- 中文名称：
- p53
- 英文名称：
- p53
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59231
- 规格：
- 5 Slides|0.1 mL (Concentrate)|3 mL (RTU)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议：
- Store at 2-8°C.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Paraffin, Frozen; Human, Cat, Cattle, Horse, Sheep
- 应用：
- IHC (Immunohistochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2b/K
克隆号:[DO7]
特异性:N/A
纯度:N/A
形式：Anti-p53 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5,containing BSA and sodium azide as a preservative.
浓度：N/A
- 说明书：
p53 (also known as tumor protein 53 [TP53]) is a transcription factor that regulates the cell cycle and, hence, functions as a tumor suppressor. p53 has been described as the “guardian of the genome”, referring to its role in conserving stability by preventing genome mutation. p53 has many anti-cancer mechanisms. It can activate DNA repair proteins when DNA has sustained damage; it can also hold the cell cycle at the G1/S regulation point on DNA damage recognition. It can initiate apoptosis, programmed cell death, if DNA damage proves to be irreparable. p53 is central to many of the cell’s anti-cancer mechanisms. It can induce growth arrest, apoptosis and cell senescence.Mutations involving p53 have been found in a wide variety of malignant tumors, including Breast, Ovarian, Bladder, Colon, Lung, and Melanoma.
