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WT1
WT1
- 中文名称:
- WT1
- 英文名称:
- WT1
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59246
- 规格:
- 5 Slides|0.1 mL (Concentrate)|3 mL (RTU)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议:
- Store at 2 to 8 degree C in the dark.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1/K
克隆号:[6F-H2]
特异性:N/A
纯度:N/A
形式:WT1 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
浓度:N/A
- 说明书:
Summary and Explanation : Wilms’ Tumor Protein (WT1) is a suppressor gene located on Chromosome 11p13. Mutations of the WT1 gene on Chromosome 11 are observed in approximately 20% of Wilms tumors. At least half of the Wilms tumors with mutations in WT1 also carry mutations in CTNNB1, the gene encoding the proto-oncogene beta-catenin.
Wilms’ tumor is a neoplasm of the kidneys that typically occurs in children. It is also known as a Nephroblastoma. WT1 has been identified in proliferative mesothelial cells, Malignant Mesothelioma, Ovarian Cystadenocarcinoma, Gonadoblastoma, Nephroblastoma and Desmoplastic Small Round Cell Tumor. Lung Adenocarcinomas rarely stain positive with this antibody.