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STAR, RMab (EP226)
STAR, RMab (EP226)
- 中文名称:
- STAR, RMab (EP226)
- 英文名称:
- STAR, RMab (EP226)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59343
- 规格:
- 5 Slides|2x5 Slides|3x5 Slides|4x5 Slides|
- 保存建议:
- Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Mouse, Rat
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG
克隆号:[EP226]
特异性:N/A
纯度:N/A
形式:Paraffin, Frozen
STAR is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
浓度:N/A
- 说明书:
Steroidogenic acute regulatory protein (STAR) is a protein that in humans is encoded by the STAR gene. The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane.
STAR is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Low level of STAR expression in other tissues that produce steroid hormones for local use have been reported. STAR antibody is a sensitive and specific marker for Leydig cell tumor. It is useful for differential identification of sex-cord stromal tumor (SCST). Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH.