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CD117 (RM359)
CD117 (RM359)
- 中文名称：
- CD117 (RM359)
- 英文名称：
- CD117 (RM359)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59400
- 规格：
- 0.1 mL (Concentrate)|3 mL (RTU)|7 mL (RTU)|0.5 mL (Concentrate)|1 mL (Concentrate)
- 保存建议：
- Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human, Monkey, Predicted: Marmoset
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG
克隆号:[RM359]
特异性:N/A
纯度:N/A
形式：Paraffin, Frozen
CD117 is rabbit monoclonal antibody from supernatant diluted in Phosphate Buffered Saline, pH7.6, with protein base, and preserved with Sodium Azide preservative.
浓度：N/A
- 说明书：
CD117 is a tyrosine-kinase receptor for stem cell factor (SCF), also known as "steel factor" or "c-kit ligand". C-kit is a polypeptide that activates bone marrow precursors of a number of blood cells, but its receptor is also present in other cells. C-kit mutations in the interstitial cells of Cajal in the digestive tract are probably the key to Gastrointestinal Stromal Tumors (GISTs).
CD117 antibody reacts with interstitial cells of Cajal, germ cells, bone marrow stem cells, melanocytes, breast epithelium and mast cells. This receptor is found on a wide variety of tumor cells (Follicular and Papillary Carcinoma of the Thyroid, Adenocarcinomas from endometrium, lung, ovary, pancreas, breast; Malignant Melanoma, Endodermal Sinus Tumor, Small-cell Carcinoma) but has been particularly useful in differentiating Gastrointestinal Stromal Tumors (GIST) from Kaposi's Sarcoma and tumors of smooth-muscle origin.
