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Cyclin D1 (RM241)
Cyclin D1 (RM241)
- 中文名称：
- Cyclin D1 (RM241)
- 英文名称：
- Cyclin D1 (RM241)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59403
- 规格：
- 0.1 mL (Concentrate)|3 mL (RTU)|7 mL (RTU)|0.5 mL (Concentrate)|1 mL (Concentrate)
- 保存建议：
- Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human, Predicted: Mouse, Rat
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG
克隆号:[RM241]
特异性:N/A
纯度:N/A
形式：Paraffin, Frozen
Cyclin D1 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
浓度：N/A
- 说明书：
Cyclins are a family of proteins involved in the progression of cells through the cell cycle. Cyclins form a complex with their partner, cyclin-dependent kinase (Cdk), which activates the latter's protein kinase function. Cyclins are so named because they are produced or degraded as needed in order to drive the cell through the different stages of the cell cycle. When its concentrations in the cell are low, the cyclin detaches from the Cdk, inhibiting the enzyme's activity, probably by causing a protein chain to block the enzymatic site.
Cyclin D1 antibody or PRAD-1 or bcl-1 is one of the key cell-cycle regulators, and functions in association with Cdk4 and/or Cdk6 by phosphorylating the Rb protein. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including Mantle Cell Lymphomas. Cyclin D1 has been found to be overexpressed in breast carcinoma.
