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CD16 (RBT-CD16), RMab
CD16 (RBT-CD16), RMab
- 中文名称:
- CD16 (RBT-CD16), RMab
- 英文名称:
- CD16 (RBT-CD16), RMab
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59493
- 规格:
- 5 Slides|3 mL (RTU)|0.1 mL (Concentrate)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议:
- 请按照说明书指示
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG
克隆号:[RBT-CD16]
特异性:N/A
纯度:N/A
形式:This antibody is derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide.
浓度:N/A
- 说明书:
CD16 is a low affinity Fc receptor, found on the surface of natural killer (NK) cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. These receptors bind to the Fc portion of IgG antibodies which then activates NK cells for antibody-dependent cell-mediated cytotoxicity. A lack of CD16 in a given population of neutrophils may indicate prematurity, as this could be caused by a left shift due to neutrophilic leukocytosis induced by tissue necrosis or bacterial infection. The IHC of CD16 is useful in the differential identification of hepatosplenic gamma delta T-cell lymphoma and gamma delta T-cell large granular lymphocyte leukemia from other peripheral T-cell lymphomas, such as mucosal and cutaneous gamma delta T-cell lymphoma. A significant decrease can be seen in the number of granulocytes expressing CD16 in chronic myelomonocytic leukemia compared to chronic myelogenous leukemia and control bone marrow biopsy, probably related to dysgranulopoiesis.