![Mouse Anti-Parathyroid Hormone Receptor 1 [3D1.1]](/skin/notimg.webp)
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Mouse Anti-Parathyroid Hormone Receptor 1 [3D1.1]
Mouse Anti-Parathyroid Hormone Receptor 1 [3D1.1]
- 中文名称：
- Mouse Anti-Parathyroid Hormone Receptor 1 [3D1.1]
- 英文名称：
- Mouse Anti-Parathyroid Hormone Receptor 1 [3D1.1]
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59533
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- Store at 4°C for one month or in small aliquots at -20°C for longer periods. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- IHC (Immunohistochemistry), WB (Western Blot), FCM/FACS (Flow Cytometry), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:Ig
克隆号:[3979]
特异性:reacts with the human Type I hPTH/PTHrP and it does not react with the Type II receptor
纯度:Protein G purified
形式：Purified antibody in PBS + 0.1% sodium azide
浓度：0.1mg/ml
- 说明书：
3D 1.1 reacts with the human Type I hPTH/PTHrP and it does not react with the Type II receptor. The antibody has been used in immunochemical studies of human ovarian tissues to demonstrate a novel role for PTH and/or PTHrP in ovarian function.
3D 1.1 recognises proteins with apparent molecular weights of 80,000 and 160,000 daltons in western blots of celllysates. Competitive binding assays show that the epitope recognized by 3D1.1 is localized to the C-terminal region of the immunogenic peptide. Furthermore, a corresponding peptide from the related PTH receptor (hPTH2) was shown to have minimal (0.1 %) cross reactivity. Finally, F ACS analysis has also been used to show that the antibody recognizes C-21 cells, but not parental BEK cells that express only the hPTH2 receptor.
Immunohistochemical staining of fixed, paraffin-embedded tissue shows specific hPTHlPTHrP receptor expression in chondrocytes, renal tubular and glomerular epithelium, afferent and efferent renal arterioles (but not glomerulr endothelium), and vascular smooth muscle and endothelium. This finding confirms that 3 D 1.1 positively stains classical PTH target tissues.
