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Lamin A/C antibody (mAb)(Clone 3A6-4C11)
Lamin A/C antibody (mAb)(Clone 3A6-4C11)
- 中文名称:
- Lamin A/C antibody (mAb)(Clone 3A6-4C11)
- 英文名称:
- Lamin A/C antibody (mAb)(Clone 3A6-4C11)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59822
- 规格:
- 0.01 mL|0.05 mL|0.1 mL|2x0.1 mL|3x0.1 mL
- 保存建议:
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.
Shipping Temp: Dry Ice
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Hamster, Human, Monkey, Mouse, Rat
- 应用:
- WB (Western Blot), IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), ChIP (Chromatin immunoprecipitation)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG2a
克隆号:[3A6-4C11]
特异性:N/A
纯度:Culture Supernatant
形式:Cell culture supernatant containing mouse IgG, 30% glycerol, 0.035% sodium azide. Sodium azide is highly toxic.
浓度:N/A
- 说明书:
Short Description: Our Lamin A/C antibody (mAb)(Clone 3A6-4C11) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation, Immunocytochemistry, Immunofluorescence, Immunoprecipitation and Western blot; it has been shown to react with Hamster, Human, Monkey, Mouse and Rat samples.
Background: Nuclear lamins are intermediate filament proteins that are the major structural component of the nuclear lamina on the inner surface of the nuclear envelope. Lamins A and Lamins C are splice variants of the Lamin A gene. Lamin A/C (CDCD1, LMN1, EMD2) expression is a hallmark of embryonic stem cell differentiation. In addition to adding structural integrity to the nucleus, lamins contribute to the makeup of the nuclear matrix. Lamins also help organize interphase chromatin through interactions with several chromatin proteins, including histones and Lap2, such that alteration in lamin organization results in disruption of DNA replication, transcription and RNA processing.