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Histone H3K14bz antibody (pAb)
Histone H3K14bz antibody (pAb)
- 中文名称:
- Histone H3K14bz antibody (pAb)
- 英文名称:
- Histone H3K14bz antibody (pAb)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59859
- 规格:
- 0.01 mL|0.05 mL|0.1 mL|2x0.1 mL|3x0.1 mL
- 保存建议:
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Wide Range Predicted
- 应用:
- WB (Western Blot), DB (Dot Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:N/A
纯度:Affinity Purified
形式:70mM Tris, 105mM NaCl, 0.07mM EDTA, 31mM glycine, 0.035% sodium azide, 0.35mg/mL BSA, and 30% glycerol.
浓度:N/A
- 说明书:
Short Description: Our Histone H3K14bz antibody (pAb) was raised in a Rabbit host. It has been validated for use in Dot blot and Western blot; it is predicted that it will react with a wide range of sample types.
Background: Histone H3 is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points. Histone H1 is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation. More recently, the identification of the lysine benzoylation (Kbz) has been shown to be associated with gene expression and to have physiological relevance that is distinct from other histone modifications. Benzoylation can be induced by sodium benzoate, which is a widely used chemical food preservative and FDA-approved drug, generating an interest in the impact of chemical preservatives on histone modification and the potential effect of metabolite-direct modifications on cellular metabolism.