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5-Methylcytosine (5-mC) antibody (mAb)(Clone 33D3)
5-Methylcytosine (5-mC) antibody (mAb)(Clone 33D3)
- 中文名称:
- 5-Methylcytosine (5-mC) antibody (mAb)(Clone 33D3)
- 英文名称:
- 5-Methylcytosine (5-mC) antibody (mAb)(Clone 33D3)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59905
- 规格:
- 0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg|5x0.05 mg
- 保存建议:
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 应用:
- IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), FCM/FACS (Flow Cytometry), ELISA, DB (Dot Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG
克隆号:[33D3]
特异性:N/A
纯度:Protein A Chromatography
形式:Purified IgG in 10mM phosphate, 0.15 M NaCl and 0.01% thimerosal. Thimerosal is highly toxic.
浓度:1ug/ul
- 说明书:
Short Description: Our 5-Methylcytosine (5-mC) antibody (mAb)(Clone 33D3) was raised in a Mouse host. It has been validated for use in Dot blot, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Methyl DNA Immunoprecipitation; it has been shown to react with Human samples, but the sequence is not species specific so it should react with a wide range of sample types.
Background: 5-Methylcytosine (5-Methylcytidine) is a modified base that is found in the DNA of plants and vertebrates. DNA methylation is an epigenetic event in which DNA methyltransferases (DNMTs) catalyze the reaction of a methyl group to the fifth carbon of cytosine in a CpG dinucleotide. This modification helps to control gene expression and is also involved in genomic imprinting, while aberrant DNA methylation is often associated with disease. The 5-methylcytidine antibody (Clone 33D3) has been developed to discriminate between the modified base and its normal cytosine counterpart, allowing for gene promoter methylation analysis.