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RBPJ antibody (mAb)(Clone 1F1)
RBPJ antibody (mAb)(Clone 1F1)
- 中文名称：
- RBPJ antibody (mAb)(Clone 1F1)
- 英文名称：
- RBPJ antibody (mAb)(Clone 1F1)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA60039
- 规格：
- 0.01 mg|0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg
- 保存建议：
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul
- 货期：
- 6-8周
- 来源宿主：
- Rat
- 反应种属：
- Human, Mouse
- 应用：
- EMSA (Electrophoretic Mobility Shift Assay), IF (Immunofluorescence), ICC (Immunocytochemistry), ChIP (Chromatin immunoprecipitation)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2b
克隆号:[1F1]
特异性:N/A
纯度:Protein G Chromatography
形式：Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
浓度：1ug/ul
- 说明书：
Short Description: Our RBPJ antibody (mAb)(Clone 1F1) was raised in a Rat host. It has been validated for use in Chromatin Immunoprecipitation, Immunocytochemistry, Immunofluorescence and Supershift; it has been shown to react with Human and Mouse samples.
Background: RBPJ (Recombination Signal Binding Protein For Immunoglobulin Kappa J Region) is a transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.
