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Calpain I (large subunit, p80)
Calpain I (large subunit, p80)
- 中文名称:
- Calpain I (large subunit, p80)
- 英文名称:
- Calpain I (large subunit, p80)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA60490
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human, Mouse, Rat, Bovine
- 应用:
- ELISA, IP (Immunoprecipitation), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1
克隆号:[15C10]
特异性:N/A
纯度:Protein A/G Chromatography
形式:Provided as a solution containing phosphate buffered saline, 0.08% sodium azide and 50% glycerol.
浓度:N/A
- 说明书:
The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and -calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kD subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar (mM) levels of calcium, -calpain is active at micromolar (uM) concentrations of Ca ++. In addition to the ubiquitously expressed m- and calpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.