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beta-Catenin (44C6) Mouse mAb
beta-Catenin (44C6) Mouse mAb
- 中文名称:
- beta-Catenin (44C6) Mouse mAb
- 英文名称:
- beta-Catenin (44C6) Mouse mAb
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA62294
- 规格:
- 0.05 mL|0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL
- 保存建议:
- Store at -20 degree C. Stable for one year from the date of shipment.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human, Mouse, Rat
- 应用:
- IHC (Immunohistochemistry), IF (Immunofluorescence), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1
克隆号:N/A
特异性:beta-Catenin (44C6) Mouse mAb detects endogenous levels of total beta-catenin protein.
纯度:N/A
形式:N/A
浓度:N/A
- 说明书:
The catenins, alpha, beta and y, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. alpha-catenin was initially described as an E-cadherin
associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. beta-catenin has also been found in complexes with the tumor suppressor protein APC. y-catenin, also known as plakoglobin, is a protein that binds with alpha-catenin and N-cadherin. It has been shown that the
transmembrane phosphatase PTP u associates with catenin/cadherin complexes and may regulate complex signaling.