p53 Tumor Suppressor Protein Mouse Monoclonal Antibody-p53 Tumor Suppressor Protein Mouse Monoclonal Antibody-一抗检测抗体

: p53 Tumor Suppressor Protein Mouse Monoclonal Antibody

p53 Tumor Suppressor Protein Mouse Monoclonal Antibody

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规格：: 0.02 mg (With BSA & Azide at 0.2mg/mL)|0.1 mg (Without BSA & Azide at 1mg/mL)|0.1 mg (With BSA & Azide at 0.2mg/mL)|5x0.1 mg (With BSA & Azide at 0.2mg/mL)|5x0.1 mg (Without BSA & Azide at 1mg/mL)

保存建议：: Antibody with azide - store at 2-8°C.
Antibody is stable for 24 months. Non-hazardous.

应用：: IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)

其他：: 克隆性:Monoclonal
同型:Mouse/ IgG2a+ Mouse/ IgG2b/ kappa
克隆号:[BP53-12 + DO-7]
特异性:Recognizes a 53kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 under denaturing and non-denaturing conditions. Its epitope maps within the N-terminus (aa 20-25) of p53 oncoprotein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
纯度:N/A
形式：200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide.
浓度：N/A