TNF-alpha-TNF-alpha-一抗检测抗体 - 北京博蕾德生物科技有限公司

规格：: 0.02 mg (With BSA & Azide at 0.2mg/mL)|0.1 mg (Without BSA at 1mg/mL)|0.1 mg (With BSA & Azide at 0.2mg/mL)|5x0.1 mg (Without BSA at 1mg/mL)|5x0.1 mg (With BSA & Azide at 0.2mg/mL)

保存建议：: Antibody without Azide - store at -20 to -80 degree C. Antibody is stable for 24 months.

应用：: IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)

其他：: 克隆性:Monoclonal
同型:IgM, kappa
克隆号:[SPM543]
特异性:Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
纯度:N/A
形式：200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
浓度：N/A