Cytokeratin 17 (KRT17) (Basal Epithelial Marker) Mouse Monoclonal Antibody-Cytokeratin 17 (KRT17) (Basal Epithelial Marker) Mouse Monoclonal Antibody-一抗检测抗体

: Cytokeratin 17 (KRT17) (Basal Epithelial Marker) Mouse Monoclonal Antibody

Cytokeratin 17 (KRT17) (Basal Epithelial Marker) Mouse Monoclonal Antibody

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中文名称：: Cytokeratin 17 (KRT17) (Basal Epithelial Marker) Mouse Monoclonal Antibody

英文名称：: Cytokeratin 17 (KRT17) (Basal Epithelial Marker) Mouse Monoclonal Antibody

规格：: 0.02 mg (With BSA & Azide at 0.2mg/mL)|0.1 mg (With BSA & Azide at 0.2mg/mL)|0.1 mg (Without BSA & Azide at 1mg/mL)|5x0.1 mg (With BSA & Azide at 0.2mg/mL)|5x0.1 mg (Without BSA & Azide at 1mg/mL)

保存建议：: Antibody without azide - Store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

应用：: IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)

其他：: 克隆性:Monoclonal
同型:IgG2b, kappa
克隆号:[E3; same as Ks17.E3]
特异性:Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as -epithelial stem cell- marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
纯度:N/A
形式：200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
浓度：N/A