CD95 / FAS / TNFRSF6 Mouse Monoclonal Antibody-CD95 / FAS / TNFRSF6 Mouse Monoclonal Antibody-一抗检测抗体

: CD95 / FAS / TNFRSF6 Mouse Monoclonal Antibody

CD95 / FAS / TNFRSF6 Mouse Monoclonal Antibody

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规格：: 0.02 mg (With BSA & Azide at 0.2mg/mL)|0.1 mg (With BSA & Azide at 0.2mg/mL)|0.1 mg (Without BSA & Azide at 1mg/mL)|5x0.1 mg (With BSA & Azide at 0.2mg/mL)|5x0.1 mg (Without BSA & Azide at 1mg/mL)

保存建议：: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

应用：: IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), FA (Functional Assay)

其他：: 克隆性:Monoclonal
同型:IgG1, kappa
克隆号:[B-R18]
特异性:MAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.
纯度:N/A
形式：200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
浓度：N/A