AKT1 (Proto-Oncogene)-AKT1 (Proto-Oncogene)-一抗检测抗体 - 北京博蕾德生物科技有限公司

规格：: 0.02 mg (With BSA & Azide at 0.2mg/mL)|0.1 mg (Without BSA & Azide at 1mg/mL)|0.1 mg (With BSA & Azide at 0.2mg/mL)|5x0.1 mg (With BSA & Azide at 0.2mg/mL)|5x0.1 mg (Without BSA & Azide at 1mg/mL)

保存建议：: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

其他：: 克隆性:Monoclonal
同型:IgG2b, kappa
克隆号:[AKT1/2491]
特异性:Recognizes a protein of 62kDa, which is identified as AKT1The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB? or RacPK-?) and Akt 3 (also designated PKB? or thyoma viral proto-oncogene 3), which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. All members of the Akt family have a Pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-? tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1(IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin.
纯度:N/A
形式：200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
浓度：N/A