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HPV11 E6 Polyclonal Antibody
HPV11 E6 Polyclonal Antibody
- 中文名称：
- HPV11 E6 Polyclonal Antibody
- 英文名称：
- HPV11 E6 Polyclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA63049
- 规格：
- 0.6 mg|2x0.6 mg|3x0.6 mg|4x0.6 mg|5x0.6 mg
- 保存建议：
- Store at -20 degree C for long term storage. Store at 2-8 degree C for up to one month. Avoid freeze/thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Goat
- 反应种属：
- Human papilloma viruses type 11
- 应用：
- WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:Detects HPV11 E6 recombinant fusion proteins MBP-E6 and GFP-E6 expressed in transfected mammalian cells.
纯度:N/A
形式：Polyclonal antibody supplied as (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
浓度：N/A
- 说明书：
Goat polyclonal antibody to HPV11 E6. E6 is one primary oncoprotein of high risk HPV types expressed early in the HPV life cycle. After the host cell is infected viral early promoter is activated and a polycistronic primary RNA containing all six early ORFs is transcribed. This polycistronic RNA then undergoes active RNA splicing to generate multiple isoforms of mRNAs. One of the spliced isoform RNAs, E6, serves as an E7 mRNA to translate E7 protein. HPV genome integrate into host genome by disruption of E2 ORF, preventing E2 repression on E6 and E7. Thus, viral genome integration into host DNA genome increases E6 expression. The E6 protein inactivates the tumour suppressor protein, p53 and promote cellular proliferation and the chance of malignancy.
